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inflammation A localized protective response elicited by injury or destruction of tissues, which serves to destroy, dilute, or wall off both the injurous agent and the injured tissue.  The five cardinal signs of inflammation include: redness (rubor) swelling (tumor) heat (calor) pain (dolor) loss of function (functio laesa) ►click here to learn more-link provided by: www.merckvetmanual.com Related Words sign